Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their healthy eyes.
The cornea is the outer layer of the eye, which focuses light towards the retina. Since it’s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth and functional.
Unfortunately, injuries like thermal or chemical burns can damage the cornea beyond the c
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nashashmi
> The new study … investigated a new treatment called cultivated autologous limbal epithelial cells (CALEC). This involves removing stem cells from a patient’s uninjured eye, growing their population in the lab for a few weeks, then surgically transplanting them into the injured eye.
14 patients tested. 79% reported healing in 12 months.
javiramos
Can’t comment on the technical quality of this paper but wanted to highlight that the research was funded by the NIH which our government is currently chaotically gutting.
Link to paper: https://www.nature.com/articles/s41467-025-56461-1.pdf
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